Cayo Largo del Sur, or simply Cayo Largo ("Long Cay"), is a small resort island in Cuba, off the south coast of the northwestern part of the main island in the Caribbean Sea. The cay is about long and wide and is the second largest island in the Canarreos Archipelago. Cayo Largo is part of the special municipality of Isla de la Juventud.

Cayo Largo del Sur, or simply Cayo Largo ("Long Cay"), is a small resort island in Cuba, off the south coast of the northwestern part of the main island in the Caribbean Sea. The cay is about long and wide and is the second largest island in the Canarreos Archipelago. Cayo Largo is part of the special municipality of Isla de la Juventud.